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Table 3 Primary outcome: infection in childbirth related perineal tears (CRPT) up to one month after delivery

From: The PLUS study: efficacy of triclosan coated suture (VicrylPlus®) to reduce infection in primary suture of childbirth related perineal tears - a randomized controlled trial

 

Vicryl®

exposed/total cases (%)

VicrylPlus®

exposed/total cases (%)

P value

OR (95% CI)

Adj- OR (95% CI)

Overall infection rate in CRPT except grade one tears

47/687 (6.8%)

28/702 (4%)

0.024*

0.57 (0.35–0.91)

0.55 (0.31-1.00)

First-degree tears

2/236 (0.8%)

8/205 (3.9%)

0.050*

4.75 (1.00-22.63)

NA

Second-degree tears (spontaneous and episiotomies)

44/613 (7.2%)

27/613 (4.4%)

0.050*

0.60 (0.36–0.98)

0.63 (0.34–1.15)

Spontaneous second-degree tears

Episiotomies

24/502 (4.8%)

14/507 (2.8%)

0.100*

0.57 (0.29–1.11)

0.73 (0.33–1.60)

20/111 (18%)

13/106 (12.3%)

0.261*

0.64 (0.30–1.35)

0.56 (0.20–1.62)

Third-degree tears

2/14 (14.3%)

1/19 (5.3%)

0.561*

0.33 (0.03–4.10)

NA

Unclassified (except grade one CBPT)

1/60 (1.7%)

0/70 (0%)

0.462*

0.98 (0.95–1.02)

NA

  1. *Fisher’s exact test. Adjusted for maternal age, maternal body mass index, primipara, antibiotic, non-steroid-anti-inflammatory-drug, GBS infection, and delivery mode