Safety and efficacy of double plastic wrap in reducing insensible water loss in preterm infants in first week of life – a pilot randomized controlled trial from a low-to-middle-income country

Table 5 Outcomes till hospital discharge

Outcome	Single wrap (n = 32)	Double wrap (n = 31)	p value
Percentages of maximum postnatal weight loss	9.06 ± 4.39	8.03 ± 4.65	0.373
Requirement of mechanical ventilation	8 (25%)	13 (41.94%)	0.247
Culture positive sepsis	7 (21.88%)	9 (29.03%)	0.717
Pneumonia	2 (6.25%)	3 (9.68%)	0.672
hsPDA	5 (15.62%)	13 (41.94%)	0.027*
Pulmonary haemorrhage	4 (12.5%)	9 (29.03%)	0.19
Acute kidney injury	4 (12.5%)	9 (29.03%)	0.129
Intraventricular haemorrhage	1 (3.12%)	5 (19.35%)	0.104
Any ROP^¶	16/28(57.14%)	13/21(61.9%)	0.777
ROP requiring treatment^¶	6/28 (21.43%)	3/21 (14.28%)	0.714
BPD^Δ	14/27 (51.85%)	8/21 (38.09%)	0.393
NEC	1 (3.12%)	2 (6.45%)	0.613
Mortality^€	5 (15.63%)	10 (32.26%)	0.148

*Statistically significant. ^¶28 infants in single wrap group and 21 infants in double wrap group were assessed for ROP. ^Δ27 infants in single wrap and 21 infants in double wrap group were assessed for BPD. ^€4 infants in single wrap and 2 infants in double wrap group did not reach their final outcome till the end of the study period. hsPDA – haemodynamically significant patent ductus arteriosus, ROP – retinopathy of prematurity, BPD- bronchopulmonary dysplasia, NEC – necrotising enterocolitis

ISSN: 2054-958X